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What is Utrogestan used for?

Utrogestan capsules are used as part of hormone replacement therapy (HRT) for the menopause in women who still have their womb. They are prescribed to be taken alongside oestrogen-based HRT to oppose the effect of the oestrogen on the womb lining.

Key facts about Utrogestan capsules

  • Utrogestan capsules are not a contraceptive.
  • Utrogestan is a brand name for progesterone.
  • You take Utrogestan on a few days each month: either two capsules every day on days 15 to 26, or one capsule every day on days 1 to 25.
  • The capsules may make some women feel dizzy or drowsy, so they are best taken at bedtime. Avoid driving or operating machinery if affected.
  • The most common side effects of Utrogestan are a change in your period and headaches.
  • You should see your doctor at least once a year for a check-up and to review your need for HRT.

How do Utrogestan capsules work?

In women who still have their womb (ie if you’ve not had a hysterectomy), oestrogen-based HRT can stimulate the growth and build-up of the womb lining (endometrium). This can lead to a slightly increased risk of developing endometrial cancer if the growth is unopposed.

The progesterone in Utrogestan capsules works by opposing oestrogen’s effect on the womb lining. It causes the womb lining to be shed, like a period, which reduces the risk of developing endometrial cancer. Utrogestan capsules are taken as part of each monthly oestrogen cycle.